Every episode, with the full transcript. Newest first.
EP 53 · Oct. 20, 2026
Amy and Whitney explain why fashion rules are made up and share style icons who prove confidence beats any dress code.
EP 52 · Oct. 13, 2026
Whitney makes the case for play in midlife after an e-bike trip through Provence, and shares how her daughter talked her way out of an attack on a trail.
EP 51 · Oct. 6, 2026
Amy learns her breakouts are actually rosacea and shares what she found on triggers, hormones and treatments, after Whitney's surprise eyelid surgery.
EP 50 · Sept. 29, 2026
Whitney shares what a remote energy healing session taught her about feeling stuck in midlife, and Amy reveals she is a Reiki master.
EP 49 · Sept. 22, 2026
Amy is on day three of the ProLon Fasting Mimicking Diet and walks Whitney through autophagy, the research behind it, the cost, and how it actually feels.
EP 48 · Sept. 15, 2026 · 31:30
Amy hits a 3 AM cortisol spike and starts spiraling about everything at once. Whitney explains why it happens and shares five habits to keep it in check.
EP 47 · Sept. 8, 2026 · 47:20
Amy walks Whitney through the many types of magnesium, what research says it can and cannot do for sleep, mood, and bones in midlife, and how much women need each day.
EP 46 · Sept. 1, 2026 · 24:01
Amy and Whitney share what happened when they took semaglutide and tirzepatide and when Whitney tried retatrutide, from food noise and side effects to muscle loss and shame.
EP 45 · Aug. 25, 2026 · 38:33
Amy walks Whitney through what fascia is and why it matters after years of using a FasciaBlaster, and Whitney reviews a $100 Korean herbal pill that came in a gold box.
EP 44 · Aug. 18, 2026 · 27:50
Whitney outlines the bare minimum for fitness, balance, bone density, and nutrition to live a long, healthy life, even for the lazy.
EP 43 · Aug. 11, 2026 · 51:38
Amy shares her extensive personal experience with ketamine therapy, covering professional IV and intramuscular treatments, nasal spray, and even an accidental k-hole.
EP 42 · Aug. 4, 2026 · 38:07
Whitney details the surprising history of Methylene Blue, from its origins as a dye to its current use as a brain-boosting biohack, while Amy shares her experience with the blue substance.
EP 41 · July 28, 2026 · 35:24
Amy and Whitney discuss pregnenolone, a foundational building block for steroid hormones, and its potential benefits for brain function, sleep, and stress control for midlife women.
EP 40 · July 21, 2026 · 41:58
Amy and Whitney wrap up Whitney's five-part MAX Life Protocol series on Arthur Brooks' happiness research with daily deposits into a happiness pension plan and the math of wanting less.
EP 39 · July 14, 2026 · 35:35
Amy reveals she has stopped taking DHEA after researching its effects, finding conflicting information and questioning her own dosage and prescription.
EP 38 · July 7, 2026 · 37:34
Whitney covers "The Pivot Protocol," epistemic humility, and understanding ego in the quest for happiness, explaining how to process reality and avoid stalling out.
EP 37 · June 30, 2026 · 38:22
Progesterone is often called the pregnancy hormone. Amy and Whitney look at what it does for mood, the brain and bones in midlife, perimenopause and menopause.
EP 36 · June 23, 2026 · 1:01:13
Amy and Whitney discuss the link between community, longevity and happiness, using Arthur Brooks' Friends Pillar to look at how to build deep, meaningful friendships.
EP 35 · June 16, 2026 · 57:58
Amy and Whitney discuss why testosterone is crucial for women's health, covering its effects on menopause and perimenopause, optimal levels, and why it matters.
EP 34 · June 9, 2026 · 54:39
Whitney shares Arthur Brooks' four pillars for a balanced happiness portfolio, explaining how diversifying energy across faith, family, friends, and work is essential for true happiness.
EP 33 · June 2, 2026 · 39:44
Amy explains the three major forms of estrogen, how smoking weed affects hormone balance, and what happens when your body's levels fluctuate wildly.
EP 32 · May 26, 2026 · 36:18
Amy and Whitney discuss Arthur Brooks' concept of the Second Curve, contrasting youthful fluid intelligence with the wisdom and experience of crystallized intelligence for true happiness.
EP 31 · May 19, 2026 · 39:27
Amy shares her two personal experiences with Ultherapy, a non-surgical cosmetic treatment that tightens skin and builds collagen. She also addresses concerns about it melting facial fat.
EP 30 · May 12, 2026 · 28:33
Whitney explains why ovaries age two and a half times faster than other organs, the scarring she says drives menopause, and what may slow it. Amy and Whitney also try an NAD nasal spray.
EP 29 · May 5, 2026 · 52:22
Amy covers NAD and its most optimal forms, Whitney explains why she ordered an NAD nasal spray, and they play "Bio-Hack or Whack" and focus on NAD for midlife women.
EP 28 · April 28, 2026 · 40:25
Whitney walks Amy through biostimulators like Sculptra and Radiesse, how they work and how long they last, and her own experience with Sculptra and PDO threads.
EP 27 · April 21, 2026 · 49:33
Amy breaks down the differences between Botox, Dysport, Xeomin, Jeuveau, Daxxify, and Letybo, helping listeners understand when and where to use each neurotoxin.
EP 26 · April 14, 2026 · 1:01:45
Amy and Whitney discuss the ancient practice of sauna bathing, its health benefits, and how to incorporate it into a midlife wellness routine.
EP 25 · April 7, 2026 · 44:24
Whitney gets Amy on the K-Beauty train and shares that salmon DNA is 95% identical to human DNA. They discuss glass skin, top products, and what it all means in the K-Beauty world.
EP 24 · March 31, 2026 · 40:41
Amy and Whitney discuss Metformin, a diabetes drug now studied for off-label uses like anti-aging, cancer prevention, and neuroprotection. They also ask if it's right for everyone.
EP 23 · March 24, 2026 · 34:50
Whitney reveals how historical beauty trends involved lead paint, urine mouthwash, arsenic wafers, and even tapeworms, making Amy question current beauty practices.
EP 22 · March 17, 2026 · 42:08
Amy answers Whitney's questions about menopause, including whether a cycle continues, how long perimenopause lasts, what post-menopause is and what vaginal atrophy means.
EP 21 · March 10, 2026 · 38:00
Whitney explains what collagen is, why it matters for skin, joints, bones and organs, and how the body loses it, and Amy and Whitney weigh whether supplements are worth the money.
EP 20 · March 3, 2026 · 39:55
Amy is taking daily wheatgrass shots and shares why, discussing its benefits for blood sugar, antioxidants, gut health, and energy, and separates science from wellness folklore.
EP 19 · Feb. 24, 2026 · 44:38
Whitney shares her experience with the BBL Heroic light treatment and a Stanford study she read suggesting regular BBL can make skin cells behave more like younger skin.
EP 18 · Feb. 17, 2026 · 56:19
Whitney's unexpected crown turns into a close look at oral health. Amy and Whitney connect flossing to longevity, and how your mouth affects your entire body.
EP 17 · Feb. 10, 2026 · 52:35
Amy and Whitney break down the latest breakthrough in sustained topical oxytocin, what it does, and natural ways to boost the "love hormone" without turning life into a science experiment.
EP 16 · Feb. 4, 2026 · 53:30
Amy and Whitney discuss neurocosmetics, skin and body care products said to act on the nervous system through the skin-brain axis, and whether their mood claims hold up.
EP 15 · Jan. 27, 2026 · 40:27
Amy and Whitney sort through the latest midlife wellness trends for 2026, including fiber maxing, Japanese walking, and the Wolverine Stack, while ditching ice baths and blue light glasses.
EP 14 · Jan. 20, 2026 · 43:28
Amy and Whitney discuss why creatine, a supplement often associated with gym bros, is having a midlife glow-up, covering its benefits for muscle, brain power, and energy.
EP 13 · Jan. 13, 2026 · 53:39
Amy and Whitney unpack impostor syndrome, why it often gets louder in midlife, and how trying new things can make you feel like a total fraud. They break down the five archetypes.
EP 12 · Jan. 6, 2026 · 39:51
Amy and Whitney unpack what glutathione is, why midlife bodies suddenly care, and whether it is worth it when no one can even agree on the best way to take it.
EP 11 · Dec. 30, 2025 · 34:22
Amy and Whitney investigate hydrogen water, a wellness trend that claims to reduce inflammation and protect brain cells. Is it legit or just another scam?
EP 10 · Dec. 23, 2025 · 46:40
Amy reports on pumpkin seeds, which her nutritionist and blood work provider both recommended, and how they may support hormones, bones, cholesterol, sleep and metabolic health.
EP 09 · Dec. 17, 2025 · 41:25
Whitney shares how PEMF and red light sessions at Upgrade Labs cleared up her sore elbow, and Amy recalls meditating on the HigherDOSE PEMF mat she has at home.
EP 08 · Dec. 9, 2025 · 52:05
Amy gives her research report on ashwagandha, an adaptogen, covering when to take it, its possible effects on stress, sleep, menopause and sex, and why thyroid patients need care.
EP 07 · Dec. 2, 2025 · 43:11
Whitney shares her experience with Fluorouracil, a topical chemotherapy cream she calls "zombie cream," describing the painful process of using it to treat precancerous skin cells.
EP 06 · Nov. 25, 2025 · 1:24:43
Amy looks back on three and a half years without alcohol, and how it led to better moods, clearer thinking, and a feeling of being "high all the time."
EP 05 · Nov. 18, 2025 · 1:08:36
Amy and Whitney share their DIY beauty habits, from brow shaping and box hair color to at-home dermaplaning and red light masks, plus what Amy says to leave to professionals.
EP 04 · Nov. 12, 2025 · 43:57
Amy humble-brags about already fibermaxxing while Whitney, who mostly eats steak tacos and kimchi, looks for easy ways to add fiber, from bean dip to cooled potatoes.
EP 03 · Nov. 5, 2025 · 50:20
Whitney has been quietly making what she calls baby wigs in the shower. This is the full account of what she tried, in order, and what it cost her.
EP 02 · Oct. 29, 2025 · 47:35
Two wedding rings lost at the same wedding, a backpack recovered from a bush, and a song on the radio at exactly the right wrong moment.
EP 01 · Oct. 29, 2025 · 39:49
The first episode, in which two friends decide midlife has got far too complicated and start with the one thing neither of them will compromise on.
